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Consult your healthcare provider for guidance on using both approaches simultaneously

For metabolism of NR, NRK1 is expressed in most tissues but is absent in the spleen and white adipose tissue, while NRK2 is only present in skeletal muscle, heart, and white adipose tissue (WAT) 40

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It may be considered when a shorter-acting GLP-1, daily dosing or a specific insurance formulary makes it a reasonable choice

Barnes PJ