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The biosynthetic capacity of humans to produce taurine is limited in neonates (the effect amplified by prematurity) and also declines with aging and some pathological stages (trauma, sepsis)

Mant CT, Hodges RS

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It also indicated directional differences between symptomatic patients and asymptomatic V30M carriers ( p = 0.0297), as well as between asymptomatic V30M carriers and healthy controls ( p = 0.0477