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In short, there are several reasons why more people and providers are experimenting with microdosing, ranging from cost and access challenges to adverse side effects at standard doses, as well as off-label uses such as appetite suppression, management of acute and chronic inflammation, impulse control, and adjunctive support in type 1 diabetes

Novo Nordisks oral semaglutide is a GLP-1 analogue taken once daily as a tablet, which would be more convenient for patients than treatments administered by injections

Oxidative stress is an imbalance between free radicals (unstable molecules that can damage cells) and antioxidants

Its ability to tighten depends on collagen (the protein that gives skin its structure) and elastin (the protein that gives skin its bounce), both of which weaken with age

10.1016/j.immuni.2017.03.019 31

doi: 10.1097/MLR.0000000000000096