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Pathway 4 Amylin (Cagrilintide) Amylin receptors (AMY1R, AMY3R heterodimers of the calcitonin receptor with RAMP1/RAMP3) are activated primarily in the area postrema, with secondary action in the NTS (Lau et al., 2021)

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Oldfield et al., 2005)

BPC157 also appears in studies to play a key role in protecting the gastrointestinal lining, and gut-wall integrity, with research into gutbrain interactions, making it of particular interest in clinical trials related to managing leaky gut, Crohns disease, and NSAID-induced ulcers