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Chen, S., Sun, Y., Lin, X

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Together, these antioxidants inhibit tyrosinase, decrease production of eumelanin, and promote the formation of lighter pheomelanin

Research also notes that natural levels show a GHK-Cu decline with age, with levels falling by about 60% by age 60, a pattern linked to reduced healing, skin health, and regenerative capacity in the human body

PMID: 28522602

The SLC22A4 transporter also functions in the renal reabsorption of ergothioneine in the kidney, with avid absorption and retention of ergothioneine from the diet observed in both animals and humans