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It is a synthetic derivative of ACTH(4-10), the fragment of adrenocorticotropic hormone responsible for neurotropic rather than hormonal effects

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A review of participation in clinical research funded by different NIH institutes and centers revealed that participation by females has been steadily increasing over 20132018 for which data are available (no data were reported in 2015, but reporting requirements changed in FY 2016, resulting in an increase in participants reported across NIH institutes and centers)

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