Increased risks of heart attacks: Hormone treatments (e.g., testosterone) increase the risk of heart attack, stroke, and blood clots.Cancer risk: Long-term use of growth hormone or sex hormones may raise the risk of certain cancers (e.g., breast, prostate).Mood changes: Hormone imbalance can lead to mood swings, anxiety, or depression.Illegal use: Some medications, like human growth hormone (HGH), are illegal for anti-ageing use and carry legal risks.Poor regulation of compounded drugs: Compounded drugs are not a standardised product, appear to carry some risk of contamination, possibly present in the wrong dosage, and potentially contain harmful additives.No proven long-term benefit: Many anti-ageing treatments show little or only temporary benefit, and the long-term safety of such treatments is unknown.Misleading marketing: Treatments are often marketed with claims that greatly exceed any support from scientific research.Also read | Struggling with weak nails

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Comparison of TB500 vs
Because of this and its involvement in the nervous system, Vitamin B12 can improve cognitive function, concentration and reaction time
Heating, e.g., during blanching and steaming, largely inactivates conjugases such that long-chain polyglutamyl folates are preserved
Cell 144 , 810823 (2011)