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Notably, under BSO treatment, these molecules may increase cysteine availability but should not restore GSH levels, as BSO irreversibly inhibits -glutamylcysteine synthetase (-GCS) the enzyme responsible for GSH synthesis downstream of cysteine 48
Nohesara S, Ghadirivasfi M, Mostafavi S, et al
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Rivlin RS, Pinto JT
The HealthRX.com Co-Prescribing Decision Framework Clinicians evaluating this combination should assess three domains before writing both prescriptions