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AAV was injected intraperitoneally at a dose of 4.8 10 12 v.g

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However, medical supervision is important for advanced cases

Studies have shown that activation of the GLP1 receptor downregulates the expression of NADPH oxidase NOX3 and mitochondrial superoxide dismutase SOD2, thereby reducing ROS levels, blocking the oxidative stress-induced upregulation of Beclin1 expression and increased LC3-II/I ratio, and delaying autophagosome formation [57]

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Manage regulatory and logistical complexities