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Anyone experiencing these symptoms should stop medication and seek immediate medical evaluation

Endocrinology 144 (5), 20552067

Participants who began at lower doses and increased incrementally reported better tolerability than those who escalated more rapidly

With seven additional Phase 3 readouts expected in 2026, we believe retatrutide could become an important option for patients with significant weight loss needs and certain complications, including knee osteoarthritis." An investigational once-weekly triple hormone receptor agonist, retatrutide is a single molecule that activates the body's receptors for GIP, GLP-1, and glucagon

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If the math is wrong, it gets caught before the vial is touched