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Eligibility usually requires age 18 or older, a BMI of 30 or higher (or 27 or higher with a documented comorbidity), and no current GLP-1 medication

George and neighboring communities excess weight increases the risk of type 2 diabetes, high blood pressure, abnormal cholesterol, heart disease, stroke, fatty liver disease, sleep apnea, and chronic joint pain

He also recommends adding an antioxidant in the morning and being diligent about daily sunscreen, since the skin can become more reactive during this time

The discomfort usually is at its strongest in the first 2 to 3 days where swelling and inflammation is at its peak

Increasing dosage does not speed results and may cause discomfort

GLP-1 agonists should not be used during pregnancy or breastfeeding, and effective contraception is advised for women of childbearing potential