However, most small-molecule ICD inducers, such as doxorubicin 12 and oxaliplatin 13 , are hindered by issues related to nonspecific enrichment and rapid drug metabolism
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Further isotope labeling experiments confirmed that upon GGCT overexpression, Gln is preferentially shunted to the GSH synthesis pathway, with a significantly reduced proportion entering the TCA cycle
Pharmacology 61(3):154166 Munday R, Munday CM (1999) Low doses of diallyl disulfide, a compound derived from garlic, increase tissue activities of quinone reductase and glutathione transferase in the gastrointestinal tract of the rat
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Frequently Asked Questions Is glutathione safe for long-term use