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Diabetes Care, 26 (11), 29772982

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coli BL21(DE3) was resuspended in Tris buffer (50 mM Tris and 500 mM NaCl, pH 8.0) and lysed by sonication on ice

DPP-4 inhibitors reduce HbA 1c levels and have a low risk of hypoglycaemia or other adverse events [38], except for a potential risk of hospitalisation for heart failure in the case of saxagliptin [38]

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2.2.3 Infections Due to their functional asplenia and functional immunocompromised status, patients with SCD are more vulnerable to infections with encapsulated organisms (increased bone marrow turnover and altered complement activation)