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However, up to 89% of participants taking efinopegdutide experienced gastrointestinal adverse events (mostly nausea, vomiting and diarrhoea) relative to 28% taking placebo and 60% taking liraglutide (86)

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P.PankeS.et al (2015)

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IGF-I also binds to the insulin receptor (IR) but with much lower (about 100-fold lower) affinity than to the IGF1R (Pandini et al ., 2002)

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