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Consultation with a clinician is essential in such cases

Researchers have also questioned whether the increase in cognitive or dietary restraint seen with GLP-1RAs reflects healthier control over eating or a more rigid form of food restriction that could prove harmful

The rationale is that the two agents may occupy GHRHR at slightly offset time windows, extending the total duration of pituitary stimulation within a single injection event

This increases cancer risk by two distinct mechanisms both through the promotion of chronic inflammation, and through inhibition of the acute inflammation that is important to halt tumorigenesis (anti-tumor immunity)