Furthermore, in rodents like mice and rats, stimulating the GLP-1 receptor raises cAMP in thyroid C cells, initiates the release of calcitonin, and upon longer-term exposure, is accompanied by C-cell proliferation and the formation of C-cell adenomas and (medullary thyroid) carcinomas (6)
Beneficial effects of once-daily lixisenatide on overall and postprandial glycemic levels without significant excess of hypoglycemia in type 2 diabetes inadequately controlled on a sulfonylurea with or without metformin (GetGoal-s)
Melanie Jay, MD, MS, is a professor of medicine and population health at NYU Langone Health and a physician investigator specializing in obesity
GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting
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Here are seven theoretical benefits that researchers are continuing to explore