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The number of potential disease targets obtained through searching the DisGeNET, Pharm Gkb, OMIM, and DrugBank disease databases was 988, 326, 188, and 32, respectively

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Thus, ASD is tightly associated with changes in mitochondrial structure and functions, which make these organelles a likely end effector in ASD patients with different etiology

Any future introduction of retatrutide would need to be supported by adequate prescribing infrastructure, likely within Tier 3 or Tier 4 specialist weight management services, as outlined in NHS England's obesity care pathways