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doi: 10.1152/ajpendo.00040.2006 147 ThompsonELAmberVStampGWPattersonMCurtisAECookeJHet al

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And as weve discussed, glutathione deficiency can lead to oxidative stress

The synergy between kinase inhibitors and high-dose VitC can be partly explained by increased redox imbalance, considering recent data showing that kinase inhibitors induce synergistic toxicity with low-dose H 2 O 2 in colorectal cancer cells [234]

However, significantly fewer gastrointestinal symptoms were observed in patients in the active treatment arm (97)