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Treatment with vitamin B-12 increased serum total vitamin B-12, serum holoTC, and c-B12, and reduced plasma tHcy and serum MMA ( P 50% lower holoTC concentration compared with vitamin B-12deficient participants with nonelevated folate ( Figure 8 A)

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Keywords: Pycnogenol , pine bark extract, placebo-controlled, double-blind, antioxidant, anti-inflammatory, endothelial health, cardiovascular 1 Introduction There are many pine bark extracts on the market, from different pine tree species, from different countries and with different levels of efficacy for human health (14)