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In clinical studies, people using GLP-1 medications (especially at higher, weight-loss-approved doses like Wegovy) lost 1520% of their body weight on average over a year, alongside diet and lifestyle changes

Oral diabetes drugs such as metformin, sulfonylureas, and DPP-4 inhibitors can interact with Wegovy

(f and g) Primary APP23 mouse astrocytes were isolated and treated with etomoxir to inhibit fatty acid oxidation, which subsequently co-cultured with the primary APP23 mouse neurons with or without exendin-4

GLP-1 RAs have also shown the ability to stimulate oligodendrocyte progenitor cell differentiation (Figure 1) [17]

Int J Exerc Sci

X., Li, G