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Mechanistically, ferroptosis is driven by the accumulation of lethal phospholipid hydroperoxides (PL-OOH), primarily derived from polyunsaturated fatty acid (PUFA)-containing phospholipids

10.1016/j.ajpath.2014.03.005[Epub ahead of print]

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N-acetylcysteine for treatment of recurrent unexplained pregnancy loss

a proposed phenomenon where abrupt cessation of 200 mg/day long-term caused withdrawal-like symptoms)

Individuals with excess methylation often do not do well with this form