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Owing to the rapid degradation of GLP-1 by dipeptidyl peptidase type 4 (DPP-4), it is structurally modified into more stable GLP-1R agonists, such as liraglutide, exenatide, and dulaglutide, which share 97%, 53%, and 90% sequence homology, respectively 12

10.1016/j.cell.2006.06.050 Cell 101 YangY.XuT.ZhangY.QinX

Aumento de la produccin de colgeno y mejora de la calidad de la piel : El eje GH-IGF-1 estimulado por CJC-1295 + Ipamorelin favorece la sntesis de colgeno y la elasticidad de la piel

References Sloan, G., Selvarajah, D

Mounjaro is a once-weekly injection containing tirzepatide, which targets two hormones, GLP-1 and GIP , and it's shown the strongest average weight loss results in clinical trials, at around 22.5% over 72 weeks

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