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In summary, the study demonstrates that FOXO4-DRI effectively eliminates senescent Leydig cells, improves the testicular microenvironment, and alleviates age-related testosterone secretion insufficiency, highlighting its therapeutic potential for male late-onset hypogonadism [1]

Diabetologia 57(4):781784 Bray JJH, Foster-Davies H, Salem A, Hoole AL, Obaid DR, Halcox JPJ et al (2021) Glucagon-like peptide-1 receptor agonists improve biomarkers of inflammation and oxidative stress: a systematic review and meta-analysis of randomised controlled trials

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