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After a minimum of 8-hour overnight fast, participants will be provided with a standard breakfast (commercially available shake) containing ~500600 kcal, with approximately 51% of the energy from carbohydrate, 33% from fat, and 16% from protein

It increased cellular 'stemness' and activated multiple repair pathways simultaneouslysuggesting it works as a broad biological reset signal

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For once-weekly preparations such as semaglutide (Ozempic, Wegovy) and dulaglutide (Trulicity), the time of day is generally less critical because these long-acting formulations maintain steady drug levels throughout the week

DCX, doublecortin

Estimated to conclude on December 15, 2025, the trial assesses primary outcomes through changes from baseline in ADAS-Cog-11 and ADCS-ADL scores, measuring cognitive and functional abilities, respectively