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While these can indirectly inform potential efficacy through drug exposure data, they still do not constitute direct efficacy endpoints, which are more commonly evaluated in later phases (Phase 2/Phase 3)

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10.3389/fragi.2025.1449485 55 KordiN.SaydiA.KaramiS.Bagherzadeh-RahmaniB.MarzettiE.JungF.et al (2024)