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This therapeutic method gets rid of the plateau effect seen in single-agent treatments and gives drug companies a way to place their products differently in the competitive metabolic disease market

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Further research is needed with aging, fit, healthy subjects, measuring a variety of physiologic and metabolic endpoints to determine if the results of this case study prevail, and if so, the mechanism of any such benefits achieved

Lopez-Olivo, J

However, the body often responds better to a gradual, steady approach

Cancer Cell (2017) 32:22137.e13