The most common side effects of Wegovy include nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar) in patients with type 2 diabetes, flatulence (gas buildup), gastroenteritis (an intestinal infection) and gastroesophageal reflux disease (a type of digestive disorder)
Briefly, the primer pairs used were F: 5'-TGAAGGAGAAGGTGTCTGCGGGA-3' and R: 5'-AGGACGGTGCGGTGAGAGTG-3'
Eating smaller, low-fat meals and, for injectable formulations, timing the dose before a lighter meal or at bedtime may reduce gastrointestinal discomfort
Discuss risks/benefits with the provider Medications That May Interact: Diabetes medications (insulin, sulfonylureas): Can increase the risk of hypoglycemia (low blood sugar) Dose adjustments needed Oral hormonal contraceptives (birth control pills): Tirzepatide may decrease effectiveness, especially after the first dose and dose increases Switch to a non-oral contraceptive or add a barrier method for 4 weeks after starting and after each dose increase Other GLP-1 medications: Cannot use tirzepatide with Ozempic, Wegovy, Saxenda, Victoza, Mounjaro, Zepbound, Byetta, or Bydureon Cannot combine with other weight loss medications or supplements without provider approval Mental Health Screening During the telehealth consultation, providers screen for: History of depression Suicidal thoughts or behavior Eating disorders (binge eating disorder, bulimia, and anorexia history) GLP-1 medications carry a warning about suicidal behavior and ideation
But the past six weeks have been transformative, all thanks to a medication called semaglutide
First-month weight loss depends on starting dose, baseline metabolism, genetics, diet quality, and exercise
