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Cartilage Repair Potential (Animal Data) Evidence quality: Low (one rabbit study) In a collagenase-induced knee osteoarthritis model in rabbits, intra-articular AOD-9604 injections enhanced cartilage regeneration

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Upon further observation, the researchers hypothesized that similar to other growth hormone (GH) stimulating peptides, Ipamorelin may be a growth receptor agonist stimulating GH release through potential affinity in growth hormone receptors