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In the last few years, numerous medications, other than those mentioned earlier, have been tested in patients with hyperuricemia or gout aiming either to reduce UA level or ameliorate deleterious effect of elevated UA levels such as increased oxidative stress, inflammation and endothelial dysfunction

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Persistent Systemic Inflammation Is Associated With Poor Clinical Outcomes in COPD: A Novel Phenotype

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By these means, they hope to at least prevent metaplasia from progressing