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We also determined whether exendin 2029 modulates proton-induced TRPV1 activation via patch-clamp recordings and calcium imaging

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307,413 In terms of apoptosis inhibition, GLP-1 activates the PI3K/Akt signaling pathway, enhances the expression of the anti-apoptotic protein Bcl-2, and inhibits the activation of caspase family proteins, reducing cell apoptosis

The cells were washed with phosphate-buffered saline (PBS) and fixed with 2% paraformaldehyde for 10 min at 25 C