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Pernicious Anemia Parenteral vitamin B12 is the recommended treatment and will be required for the remainder of the patient's life

Another large-scale cohort study demonstrated that long-term GLP-1RA use was associated with a more than twofold, exposure-dependent increase in the risk of developing nAMD

However, for other conditions like atherosclerotic disease and stroke, observational and Mendelian-randomization evidence is mixed, with studies showing positive, inverse, or null associations depending on the specific endpoint

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Side effects sometimes necessitate discontinuation

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