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Introduction Immune checkpoint inhibitors (ICIs) have revolutionized the management of several advanced cancers ( Figure 1 ) ( Figure 1 ICIs activate T cells and are often associated with a large spectrum of autoimmune responses, which are commonly referred to as immune-related Adverse Events (irAEs)

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1.78 million particles in the third class were cleaned up by heterogeneous refinement and then further subjected to 3D classification

10.1007/s10545-016-0010-6 211 RobisonG.SullivanB.CannonJ