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This conversation should address your diabetes control (if applicable), weight management goals, and any concerns about stopping the medication

Metabolic Stability More consistent drug levels could provide: Steady appetite suppression: Avoiding the "feast-famine" cycle of weekly dosing Consistent energy levels: Reduced fluctuation in metabolic rate Better glucose control: Continuous incretin effect rather than peaks and valleys Improved sleep: Less variation in nocturnal glucose and hunger hormones 3

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Kimura et al

In ANKO mice, a reduction in plasma eNAMPT levels suppresses hypothalamic NAD + levels and SIRT1 activity, resulting in a defect in physical activity

It says those with a history of pancreatitis, severe gastroparesis, or active thyroid disease require provider evaluation first