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Majdpour D, Tsoukas MA, Yale J-F, El Fathi A, Rutkowski J, Rene J, et al

For both trials, efficacy analyses were conducted using 13-week data from the combined CYMBALTA 60 mg and 120 mg once daily treatment groups compared to the placebo group

Results showed significant improvements in weight loss, blood pressure, and lipid profiles among participants

This effect was inhibited by the GLP-1 antagonist exendin (939), suggesting that OXM may act through the GLP-1 receptor (GLP-1R) to regulate food intake

This reflects a desire for clear dose-to-volume relationships in metabolic studies

Store in original sealed vials, protected from light