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doi:10.1056/NEJMoa2107519 25

Abstract Hypoxia drives diabetic kidney disease (DKD) progression through Hypoxia Inducible Factor (HIF) signaling

13 Journal of Medicinal Chemistry (ACS)Bisubstrate inhibitors of NNMT with enhanced activity

These side effects are generally mild to moderate, transient, and improve within the first few weeks of therapy

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This is especially important for those with genetic polymorphisms in glutathione genes