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Analyses from our pivotal ApproaCH Trial showed that children treated with TransCon CNP had improvements in the Physical Functioning domain of the Achondroplasia Child Experience Measure (ACEM-PF), with greatest benefits in younger children who had the most pronounced leg bowing angulation (5 degrees) at baseline, supporting benefits beyond linear growth

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10.1021/acs.jmedchem.5b00726 31 Lauby-SecretanB.ScocciantiC.LoomisD.GrosseY.BianchiniF.StraifK.et al (2016)

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