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201204 ALDH2 can inhibit the activation of NLRP3 inflammasome by reducing the excessive accumulation of mitochondrial ROS (mtROS) and total intracellular ROS, thereby mitigating high glucose-induced pyroptosis in cardiomyocytes

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For chromatographic metabolite separation, a Vanquish ultra-performance liquid chromatography (UPLC) system was coupled to a Q Exactive HF (QE-HF) mass spectrometer equipped with heated electrospray ionization (HESI