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Moreover, WES allows for the integration of pharmacogenomic information, particularly exonic variants in genes related to the Absorption, Distribution, Metabolism, and Excretion (ADME) of drugs, which may complement targeted assays traditionally used to calculate pharmacogenetic profiles, with the possibility of expanding the understanding of gene-drug interactions, and indirectly inform potential drugdrug and drug-nutrient interactionswhich will necessarily have to be calculated through other platforms (Whirl-Carrillo et al., 2012)

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Biochem Pharmacol 2013;85(9):13981404