Tirzepatide is not an approved treatment for multiple sclerosis, and current evidence does not prove that it reduces relapses, MRI lesions, or disability progression
Multivariate analysis showed no difference between placebo and liraglutide arms in HbA1c at 6 months (HbA1c:0.2 mmol/mol, 11.3, 11.6, p = 0.98) however, at 12 months HbA1c was significantly higher in the liraglutide arm (HbA1c:10.9 mmol/mol, 1.1, 20.6, p = 0.032)
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Some individuals with higher starting weights respond excellently to moderate doses
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