Dimensions: 6000 x 2340 px | 50.8 x 19.8 cm | 20 x 7.8 inches | 300dpi Date taken: 10 June 2017
Withaferin A induces ROS-mediated paraptosis in human breast cancer cell-lines MCF-7 and MDA-MB-231
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This variation demonstrates that the characteristics of aging do not manifest uniformly across different organ systems
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Intracellular ROS oxidise the thiol linkages in cysteine residues of proteins including kinases and phosphatases, ultimately affecting the growth factors, cytokines, and hormones