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Further randomized controlled trials are necessary to fully evaluate its efficacy in hyperpigmentation, TEWL, skin elasticity, and ultraviolet (UV) damage
Xue et al., 2004b
Brown (U Penn School of Medicine, PA) for providing Igf1rfl/fl and UBC- CreERT2 mouse lines, respectively
It controls gene transcription in immune activation, cytokine production, cell survival, and inflammation
Work in human biopsy models has shown that IL-12p35 was not expressed within psoriatic skin lesions, whereas p40 in IL-12 and IL-23, along with IL-23p19, were significantly expressed
Total soluble protein was measured based on Bradford 64 assay at 595 nm
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