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During active weight loss or GLP-1 medication use, weekly to bi-weekly is common

(Your thumb and forefinger should be about an inch and a half apart.) This pulls the fatty tissue away from the muscle and makes the injection easier

A B12 shot is administered by injecting vitamin B12 directly into muscle tissue, typically in the upper arm, thigh, or hip

These shots are administered via intramuscular injection (often referred to as IM) so there is no gastrointestinal metabolism, which also allows for increased nutritional absorption

Older adults Adults over 50 may experience different response patterns due to age-related metabolic changes

Pregnant or breastfeeding patients should discuss with their obstetric provider before starting this injection, and ensure all healthcare team members are aware, so that vitamin levels and any pregnancy-related effects can be monitored appropriately