An example is GdW@CS polyoxometalate nanospheres, which combine radiosensitization capabilities with GSH depletion [86]
A review summarizes similar effects across mice and cashmere goats (Dai et al., 2021, DOI), and one study tested thymic peptides on cultured human hair follicles (Meier et al., 2012, DOI)
One study found older cigarette smokers had 1.8-fold less of a glutathione response to smoking compared with younger smokers
doi: 10.1136/gut.2004.059741 13 UssherJRDruckerDJ
For weight-loss surgery, the idea is that at higher BMI levels, the long-term health risks are usually greater than the risks of the procedure thats why there are cutoff numbers in place
Professional intervention becomes necessary when over-the-counter treatments fail after 12 weeks - dermatologists can safely prescribe stronger options like 4% hydroquinone or recommend laser treatments