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FIGURE 1 5 Exogenous source of antioxidants with therapeutic potential At present, there are many types of antioxidants in use, including essential oils (EO) (de Sousa et al., 2023) extracted from various plants, ALA which is used clinically to treat diabetic peripheral neuropathy (DPN), phenolic substances, vitamin C and E, MT, etc

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Glutathione is essential for the proper function of white blood cells

At normal blood glucose levels, up to 97% of glucose filtered by the glomeruli is reabsorbed by sodium-dependent glucose transporter-2 (SGLT2) in the initial segment of the tubule, and only 3% of the remaining glucose is reabsorbed by sodium-dependent glucose transporter-1 (SGLT1) in the later segment of the proximal tubule ( In summary, hyperglycemia induces renal tubules metabolic disturbances, hypoxia, oxidative stress, EMT, and programmed cell death which facilitate renal tubular injury and renal fibrogenesis

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Clinical guidance recommends testing before deciding on injections aimed at improving energy or weight