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GIPR variants influence glucose-dependent insulin secretion

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Cell Rep (2018) 23(6):175466

10.1016/j.bcp.2025.116821 32 GuoY.ZhaoY.QiaoY.XingY.FangY.ZhaoY.et al (2025b)

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Emerging multi-agonists such as retatrutide (GLP-1/GIP/glucagon triple agonist) and PTT-A (novel unimolecular peptide tetra-agonist targeting GLP-1, GIP, glucagon and amylin receptors) further expand this concept