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In addition to GLP-1 in tissues, we used ELISA to detect the level of GLP-1 in serum, and its trend was also consistent with that of GLP-1 in pancreas and intestine (Figure 3E)

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Fluctuations in estrogens levels associated with migraine produce biochemical changes in prostaglandin production, prolactin release, and endogenous opioid regulation (Dzugan 2004, 2006)

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