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doi:10.1016/0029-7844(96)00123-8 Baumgart, Juliane, et al

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In parallel with its ongoing engagement with the FDA, Aardvark intends to unblind the clinical data accumulated to date across the HERO trial to assess the totality of available efficacy and safety data and to support an informed determination of next steps for the ARD-101 program

Several factors converge at this point: sleep quality has stabilized, the body has adapted to the medication, and meaningful weight loss has occurred