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Keywords: GLP-1RAs, GLP-1/GIP dual receptor agonist, tirzepatide, clinical pharmacology, T2DM, obesity, neuroprotection Introduction Glucagon-like peptide-1 (GLP-1) is a small-peptide hormone

Description Why 5-Amino-1MQ Is Redefining Lipid Metabolism Research Selective NNMT inhibitor -35% fat mass in 11 days without appetite reduction (preclinical model) Enzymatic Target NNMT Inhibitor Selective inhibition of nicotinamide N-methyltransferase (IC50 = 1.2 M)

Biofactors 43 , 415423 (2017)