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Side effects often temporarily worsen when you increase to each new dose level

This extended half-life is one reason patients only need one injection per week, unlike shorter-acting diabetes medications that require multiple daily doses

23 Autism spectrum disorder (ASD) Autism spectrum disorder is a common neurodevelopmental disorder, characterised by reduced social communication, and restrictive and repetitive behaviours and interests

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Within-subject variability in bioavailability was 137%, which with once-daily dosing and a long half-life translates into 33% within-subject variability in steady-state exposure