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These included the -opioid (Cvejic and Devi, 1997), metabotropic glutamate (Romano et al., 1996), and 2 adrenergic (Hebert et al., 1996) receptors

In contrast, the epithelial resistance, R ep , evaluated by transmural impedance analysis, was reduced in CD patients with active disease only (118)

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Study design This was a randomized, double-blind, placebo-controlled phase 1 clinical trial assessing the safety, tolerability, pharmacokinetics, and pharmacodynamics of the GDF8 and ActA mAbs, trevogrumab and garetosmab, alone and in combination

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